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The Effect of Reality Therapy on the Serotonin Level and Depression Score in Cervical Cancer Patients

机译:现实疗法对宫颈癌患者血清素水平和抑郁评分的影响

摘要

Introduction: Cervical cancer is cancer occurring in the cervix uteri, which is mostly caused by an infection by human papillomavirus (HPV). Women diagnosed with advanced cervical cancer suffer emotional stress that can lead to depression. This condition causes decreasing quality of life, decreasing level of serotonin, and an increase in depression score. Giving reality therapy to patients is expected to have positive effects. Methods: The research was con- ducted through an experiment with pre-test and post-test design. The research samples were15 subjects taken through consecutive sampling from the Polyclinic of Obstetrics and Gynecol- ogy of Dr. Moewardi Hospital Surakarta starting in March 2015. The analysis of serotonin level was conducted in Prodia Laboratory. The experimental data was analyzed using a t-test (α =0.05). Results: The average level of serotonin of the research subjects after receiving reality therapy was higher (223.59 + 41.20) compared to that before the therapy (82.77 + 27.02). From the t-test analysis with p = 0.00, it was found that the average depression score after receiving reality therapy is lower (11:40 + 4.80) compared that before the therapy (17:33 +5:52). Conclusion: There was a significant increase in the serotonin level and a significant decrease in the depression score as the effect of reality therapy given to patients with ad- vanced cervical cancer.
机译:简介:宫颈癌是发生在子宫颈的癌症,主要是由人乳头瘤病毒(HPV)感染引起的。被诊断患有晚期宫颈癌的妇女承受着可能导致抑郁的情绪压力。这种情况导致生活质量下降,血清素水平下降和抑郁评分增加。对患者进行现实疗法有望产生积极作用。方法:本研究是通过具有预测试和后测试设计的实验进行的。研究样本为从2015年3月开始从苏拉卡塔市Moewardi医院的妇产科和妇产科综合诊所连续取样的15名受试者。血清素水平的分析在Prodia实验室进行。使用t检验(α= 0.05)分析实验数据。结果:接受实物治疗后,研究对象的5-羟色胺平均水平高于治疗前的平均水平(223.59 + 41.20)。从p = 0.00的t检验分析中,发现接受现实疗法后的平均抑郁评分(11:40 + 4.80)低于治疗前的平均抑郁评分(17:33 +5:52)。结论:由于对晚期宫颈癌患者进行了现实疗法,血清素水平显着增加,抑郁评分显着下降。

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